KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4
All Species:
26.36
Human Site:
S298
Identified Species:
38.67
UniProt:
O43172
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43172
NP_004688.2
522
58449
S298
P
K
D
V
N
L
A
S
C
A
A
D
G
S
V
Chimpanzee
Pan troglodytes
XP_520198
559
62217
S335
P
K
D
V
N
L
A
S
C
A
A
D
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001102859
521
58408
S297
Q
K
D
V
N
L
A
S
C
A
A
D
G
S
V
Dog
Lupus familis
XP_532038
521
58332
S297
Q
K
D
V
N
L
A
S
C
A
A
D
G
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAW6
521
58352
S297
Q
K
D
V
N
L
A
S
C
A
A
D
G
S
V
Rat
Rattus norvegicus
Q5BK30
415
45841
S196
S
T
V
V
A
T
G
S
M
D
T
T
A
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518220
390
43930
G171
L
A
S
C
A
A
D
G
S
V
K
L
W
S
L
Chicken
Gallus gallus
Q5ZMA2
505
55116
S282
P
S
Q
D
L
V
F
S
A
S
P
D
A
T
I
Frog
Xenopus laevis
Q5FWQ6
415
45899
S196
S
T
L
I
A
T
G
S
M
D
T
T
A
K
L
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
S196
S
T
L
V
A
T
G
S
M
D
T
T
A
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
G191
E
C
I
K
T
M
H
G
H
D
H
N
V
S
S
Honey Bee
Apis mellifera
XP_393186
525
59172
Q291
V
V
G
E
R
A
G
Q
T
C
V
L
A
S
C
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
S273
A
I
S
A
S
A
D
S
H
I
R
V
W
S
A
Sea Urchin
Strong. purpuratus
XP_795434
502
56264
S278
P
N
A
C
C
M
A
S
C
S
A
D
G
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22212
554
61823
A314
S
P
V
D
D
C
L
A
T
A
S
A
D
R
T
Baker's Yeast
Sacchar. cerevisiae
P20053
465
52424
F246
E
D
G
L
I
K
N
F
Q
Y
S
N
E
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
99
99.2
N.A.
98.8
25.4
N.A.
71.2
21
24.1
24.3
N.A.
22.2
58.2
22
62
Protein Similarity:
100
93.1
99.2
99.6
N.A.
99.4
40.6
N.A.
73.3
41.3
41.3
41.5
N.A.
39.6
72.9
40.6
77
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
13.3
N.A.
6.6
20
6.6
13.3
N.A.
6.6
6.6
13.3
53.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
20
N.A.
13.3
46.6
20
20
N.A.
20
6.6
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.7
51.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
25
19
38
7
7
38
38
7
32
7
7
% A
% Cys:
0
7
0
13
7
7
0
0
38
7
0
0
0
0
7
% C
% Asp:
0
7
32
13
7
0
13
0
0
25
0
44
7
0
0
% D
% Glu:
13
0
0
7
0
0
0
0
0
0
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
25
13
0
0
0
0
38
0
7
% G
% His:
0
0
0
0
0
0
7
0
13
0
7
0
0
0
0
% H
% Ile:
0
7
7
7
7
0
0
0
0
7
0
0
0
0
7
% I
% Lys:
0
32
0
7
0
7
0
0
0
0
7
0
0
19
0
% K
% Leu:
7
0
13
7
7
32
7
0
0
0
0
13
0
0
25
% L
% Met:
0
0
0
0
0
13
0
0
19
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
32
0
7
0
0
0
0
13
0
0
0
% N
% Pro:
25
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
19
0
7
0
0
0
0
7
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
7
0
0
7
0
% R
% Ser:
25
7
13
0
7
0
0
69
7
13
13
0
0
57
7
% S
% Thr:
0
19
0
0
7
19
0
0
13
0
19
19
0
7
7
% T
% Val:
7
7
13
44
0
7
0
0
0
7
7
7
7
0
38
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _